Platelet Rich Fibrin (PRF) is a by-product of blood that is exceptionally rich in platelets. PRF has been used in hospitals to accelerate the body’s own healing process, but it has only recently been introduced into oral surgery practices. Blood platelets perform several essential functions in the body, including blood clot formation and the release of growth factors that help to heal wounds. These growth factors stimulate the stem cells to produce new host tissue as quickly as possible, which is why PRF is so effective in the post-treatment healing process.

PRF is used in Oral and Maxillofacial Surgery in the following ways:

  • Bone Grafting for Implants – this includes closure of a cleft lip and cleft palate, sinus lifts, ridge augmentation, as well as inlay and onlay grafts.
  • Bone Repair – PRF can be used in facial trauma reconstruction as well as the removal of growths and cysts.
  • Fistula Repair – This includes the repair of fistulas between the mouth and sinus cavity.


Advantages of Platelet Rick Fibrin Treatment include:

  • Lower Infection Risk – PRF is secured on the wound after the procedure by the surgeon which in turn seals the wound from any infectious agents, lowering the risk of complications after surgery.
  • Accelerated Healing – Saturating the wound with PRF helps increase tissue synthesis due to its growth factors, which in turn results in faster tissue regeneration. Speedier healing decreases the risk of later infections, complications, and discomfort.
  • Safety and Convenience – There is no chance of disease transmission since the blood is harvested from the patient’s own supply; the amount of blood needed is small too and can be obtained during a routine outpatient procedure.


Our oral surgeons will determine whether you are a candidate for PRF treatment. For example, patients with blood clotting disorders cannot take advantage of this treatment. A sample of your blood will be collected during a scheduled outpatient treatment which will be placed into a centrifuge to separate the plasma and fibrin from the red blood cells. The centrifuge concentrates the platelets, fibrin and white blood cells which contains a growth factor called Platelet Derived Growth Factor (PDGF).

Immediately after suturing the wound, your surgeon will apply a large amount of PRF to the surgical wound to accelerate healing and lessen the amount of discomfort after surgery. The surgeon will provide aftercare instructions pertaining to the surgery and a prescription for pain medication as required.